Browsing by Author "Chattaraj, S."

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Advances in Bioprocess Monitoring and Control Systems
(IGI Global Scientific Publishing, 2025-09-05) Kumar, R.; Chattaraj, S.; Gökhan Boyno, G.; Alloun, W.; Andjelković, Snežana; Živković, S.; Guerra Sierra, B. E.; Mitra, D.
The bioprocess monitoring market, valued at $12.3 billion in 2023, is expected to grow at a CAGR of 9.1% to reach $20.5 billion by 2030. This growth is driven by biosensors, machine learning, and Industry 4.0. Innovations like Raman spectroscopy and NMR have improved metabolite profiling accuracy, leading to enhanced process control. Artificial intelligence-driven models have reduced batch variability by 20%, while digital twin technologies have reduced process development time by 25%. Automated fed-batch strategies have increased recombinant protein yields by 15-25%, while microfluidic bioreactors enable high-throughput screening with a 5-fold reduction in reagent costs. Soft-sensor technologies have adjusted metabolic flux projections by 35%, reducing process variation. IoT-enabled bioprocessing has reduced manual interventions by 40%, improving operational effectiveness.
Antimicrobial resistance in Salmonella: One Health perspective on global food safety challenges
(Elsevier BV, 2025) Kumar, R.; Adeyemi, O. N.; Chattaraj, S.; Alloun, W.; Thamarsha, A.K.A.N.W.M.R.K.; Andjelković, Snežana; Mitra, D.; Gautam, P.
Antimicrobial resistance (AMR) in Salmonella is a major concern in terms of human health, environmental sustainability, and global food security. Salmonella, the world's most prevalent foodborne pathogen, has gradually gained resistance to important drugs, complicating treatment efforts and leading to rising morbidity, mortality, and economic costs. Overuse of antibiotics in human medicine and agriculture, inadequate regulatory compliance, and environmental pollution from agricultural runoff and treated sewage all contribute to the growth and spread of AMR in Salmonella. Health as well as viewpoints on environmental, animal, and human health will be required to address this complicated problem. This includes promoting reasonable antibiotic use, improving global surveillance systems, and researching novel treatments including phage therapy, probiotics, and new antibiotics. Proposals for vaccination and precise food safety standards are critical for limiting Salmonella transmission across the food chain. Despite significant progress, critical research gaps continue, specifically in understanding the molecular basis of resistance and the role of environmental practices. However, contemporary research endeavors are concentrated on identifying and comprehending the prevalence of extensively drug-resistant Salmonella strains, elucidating the bacterium's defense mechanisms against antibiotics, and investigating outbreaks associated with vegetables. Global surveillance, the development of alternative therapies, and the implementation of stricter antibiotic policies are essential strategies in addressing AMR in Salmonella. Additionally, policy design and implementation, capacity building in low- and middle-income countries, and raising public awareness all necessitate urgent global collaboration among governments, international agencies, non-governmental organizations, and the corporate sector. Stricter regulations on overuse of antibiotics in agriculture is also called for. This review highlights the importance of multi-disciplinary struggles in engaging Salmonella, as integrated resolutions through a One Health approach are crucial for ensuring food safety, preserving public health, and minimizing the worldwide threat of AMR.
Rock Phosphate Solubilizing Potential of Soil Microorganisms: Advances in Sustainable Crop Production
(MDPI AG, 2023-05-10) Trifunović, B; Nosratabad, A.F.; Mitra, D.; Chaithra, M.; Danesh Y.R.; Boyno, G.; Chattaraj, S.; Priyadarshini, A.; Andjelković, Snežana; Pellegrini, M.; Guerra-Sierra, B.E.; Sinha, S.
Phosphorus (P) is one of the most important elements required for crop production. The ideal soil pH for its absorption by plants is about 6.5, but in alkaline and acidic soils, most of the consumed P forms an insoluble complex with calcium, iron, and aluminum elements and its availability for absorption by the plant decreases. The supply of P needed by plants is mainly achieved through chemical fertilizers; however, in addition to the high price of these fertilizers, in the long run, their destructive effects will affect the soil and the environment. The use of cheap and abundant resources such as rock phosphate (RP) can be an alternative strategy for P chemical fertilizers, but the solubilization of P of this source has been a challenge for agricultural researchers. For this, physical and chemical treatments have been used, but the solution that has recently attracted the attention of the researchers is to use the potential of rhizobacteria to solubilize RP and supply P to plants by this method. These microorganisms, via. mechanisms such as proton secretion, organic and mineral acid production, siderophore production, etc., lead to the solubilization of RP, and by releasing its P, they improve the quantitative and qualitative performance of agricultural products. In this review, addressing the potential of rhizosphere microbes (with a focus on rhizobacteria) as an eco-friendly strategy for RP solubilization, along with physical and chemical solutions, has been attempted.
Smart Recycling and Sustainable Lignocellulosic Waste Management
(Springer Nature Singapore, 2025) Gupta, N.; Wijenayake, W.P.T.; Roy, D.; Kumar, R.; Rangot, M.; Chugh, P.; Santoyo, G.; Chattaraj, S.; Bhaskar, S.S.; Andjelković, Snežana; Guerra-Sierra, B.E.; Mitra, D.
Lignocellulosic waste management and smart recycling strategies are critical components of a sustainable bioeconomy and environmental stewardship. The increasing generation of lignocellulosic waste from agricultural, forestry, and industrial activities poses significant environmental and economic concerns. Conventional disposal methods such as landfilling and incineration contribute to pollution and resource depletion. In response, smart recycling techniques have emerged as viable solutions for converting lignocellulosic waste into valuable resources while minimizing environmental impact. Mechanical, chemical, and biological processes are integral to smart recycling, enabling the conversion of waste biomass into biofuels, biochemicals, biopolymers, and other high-value products. Advanced technologies such as pyrolysis, hydrothermal processing, enzymatic hydrolysis, and fermentation offer efficient pathways for lignocellulosic waste valorization, contributing to energy security and reducing greenhouse gas emissions. The integration of circular economic principles into lignocellulosic waste management promotes material reuse, recycling, and resource efficiency. This approach emphasizes the transformation of waste streams into secondary raw materials, thereby reducing dependence on finite resources and mitigating environmental degradation. Case studies and real-world applications have underscored the feasibility and scalability of smart recycling techniques across diverse waste streams and regions. However, challenges persist in terms of technological maturity, economic viability, and regulatory frameworks, necessitating interdisciplinary collaboration and policy interventions to facilitate its widespread adoption and implementation. Hence, keeping in view the necessity of the synthesis of innovative technologies, sustainable practices, and policy initiatives is imperative for advancing lignocellulosic waste management.